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    Possibility is found in unknowns. Can we use pi to make sense of life without doing any math? Pi has everyday practical has practical applications and is a real tool to better understand the universe and life itself.

    Numerically, pi is 3.14159 “plus a little bit.” It’s in the never ending infinity that hides pi’s greatest lesson, 31.4 trillion digits, plus a little bit. There is always that added bit that simply can’t be figured out no matter how much information or education we possess

    In the Americas and other indigenous cultures in the world consider 4 directions in relation to a circle. An ancient site some 6000 to 8000 years old in Manitoba suggests a possible answer to what it means.

    This result infers a gap or gaps exits where the beginning and the end are incapable of meeting.

    Does physical chemistry understand statistics? And, is this demonstrable? This is the challenge.

    Many disciplines haven’t traditionally cast analyses of living systems as optimization problems because the complexity of those systems makes them hard to quantify and recognize what needs optimization. Evolving systems can improve over time but nothing guarantees they are driven to an optimal level.

    The circle has a gap or gaps in it or possible misaligned displacement. This suggests a pattern that lays the foundation for the expression of “pair-rule.”

    If molecules get all the information they needed to define the positions of pair-rule bonding’s from the systems noise and the gap alone,  in consideration of attraction and repulsion, hence no obvious towards pairing.

    Could one consider the “gap” has an optimal Bayesian decoder as a circle decoder that uses Bayes’ rule inferring the likelihood of an event from prior conditional probabilities given the Bayesian framework? Suggesting measurements of the possible gaps, related and given position could be used to generate a “best guess” of position, given only the gap.  Optimization principles constitute a concrete idea that could help experts better understand biological systems.

    Touch your fingers together. The distance and space at the atom level is amazing because no one can.

    This is the space under consideration in the paper at a basic level. The circle has the “trim-tab” of our lives.  

  • : Barry W. Colby
  • : ASQ, U of M, CTTAM, others
  • : Barry W. Colby
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  • : bcolby@mts.net
  • : 204-888-9560
Physical Chemistry, Statistics, Circles Trim-tabs of Lives